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August 20, 2007

EHP-in-Press Reports Study on Neurotoxicity of P25 Nanomaterial

Lynn L. Bergeson

On August 3, 2007, EHP-in-Press posted an article entitled “Nanosize Titanium Dioxide Stimulates Reactive Oxygen Species in Brain Microglia and Damages Neurons, In Vitro.” The article describes the in vitro neurotoxicity of P25, a commercially available titanium dioxide nanomaterial. According to the study, P25 appears to be non-toxic to isolated N27 neurons, but stimulates BV2 microglia to produce reactive oxygen species and damages oxidative stress-sensitive neurons in cultures of brain striatum. EHP-in-Press articles have been peer reviewed and accepted for publication in Environmental Health Perspectives.