Nano and Other Emerging Chemical Technologies Blog

The Scientific Committee on Consumer Safety (SCCS) announced on October 30, 2025, that the European Commission (EC) requested a scientific opinion on the safety of hydrated silica (nano), pyrogenic silica (nano), silica silylate (nano), and silica dimethyl silylate (nano). The request states that given the continued and widespread use of these silica materials in cosmetic products, and in view of the previous inconclusive assessments by SCCS and the new submission of safety data by industry, the...

The Organisation for Economic Co-operation and Development (OECD) has published a draft guidance document on in vitro testing for intestinal fate of orally ingested nanomaterials. According to OECD, the new guidance document “would establish a conceptual framework and procedures for determining intestinal fate of orally ingested nanomaterials using an integrated in vitro approach simulating the human [gastrointestinal tract] environment.” The primary objective of the draft guidance document...

On October 21, 2025, the European Commission (EC) announced that it has called for evidence and begun a public consultation on the upcoming Advanced Materials Act, “a key initiative under the Competitiveness Compass.” According to the EC, the Act will establish a strategic framework for the development, deployment, and production of advanced materials. The EC states that advanced materials “are intentionally designed and engineered materials with innovative properties and functionalities,...

The European Union (EU) Observatory for Nanomaterials (EUON) has contracted the Nanotechnology Industries Association (NIA) and Yordas Group to undertake a study on the assessment of health and environmental hazards and risks of surface-treated nanomaterials. The aim of the study is to review and collect scientific information and data on how surface treatment can affect the properties of nanomaterials and potentially have an impact on their fate and potential risks. The study includes a market...

The Organisation for Economic Co-operation and Development (OECD) has published a September 2025 document entitled Guidance Document on Assessing the Apparent Accumulation Potential of Nanomaterials. The document is intended to provide specific advice on how to conduct bioaccumulation tests in fish with nanomaterials following Test Guideline (TG) 305 (OECD 2012), once it has been decided that such a fish test is needed. The purpose is to offer guidance on the critical points indicated in the...

The Scientific Committee on Consumer Safety (SCCS) announced on September 18, 2025, that the European Commission (EC) has requested a scientific opinion on the safety of titanium dioxide (nano and non-nano) in cosmetic products. As reported in our May 24, 2024, blog item, on May 23, 2024, SCCS published a document entitled “Scientific Advice on Titanium dioxide (TiO2).” The document noted that the available evidence was not sufficient to exclude the genotoxicity potential of almost all of...

The Particles Platform, an informal alliance of European Union (EU) industry associations representing manufacturers of materials in the form of particles, including poorly soluble low toxicity particles (PSLT), will hold a workshop on October 2, 2025. The workshop intends to advance regulatory science on particles through new evidence on inhalation toxicity. It will explore the regulatory landscape for particles and provide attendees an opportunity to: Access the latest research on particle...

The International Organization for Standardization (ISO) recently published two standards for graphene-related two-dimensional (2D) materials: ISO/TS 9651:2025, Nanotechnologies -- Classification framework for graphene‐related 2D materials: The document specifies the characteristics and their respective measurement methods of graphene-related 2D materials in sheet and particle forms for commercial applications with the aim of classification of the materials. The classification framework...

On July 23, 2025, Environment and Climate Change Canada (ECCC) announced the release of the Plan of Priorities, a multi-year plan that outlines upcoming priorities for the assessment of chemical substances. The Plan includes a list of more than 30 substances and substance groups prioritized for assessment and includes new or expanded activities to help assess, control, and manage risks posed by substances. ECCC states that in selecting and prioritizing these substances, considerations included:...

On August 1, 2025, the European Court of Justice (ECJ) issued a judgment upholding the 2022 decision of the General Court annulling the 2019 harmonized classification and labeling of titanium dioxide as a carcinogenic substance by inhalation in certain powder forms. As reported in our December 6, 2022, memorandum, the court annulled the European Commission’s (EC) decision to classify titanium dioxide as a suspected human carcinogen. The French government and the EC appealed the decision,...