Regulatory and legal developments involving nano and other emerging chemical technologies

July 10, 2025

OECD Publishes Case Study on 2D Titanium Carbide MXenes 

On June 30, 2025, the Organisation for Economic Co-operation and Development (OECD) published a report entitled 2D Titanium Carbide MXenes: Case Study Report on Advanced Materials. Within OECD’s Working Party on Manufactured Nanomaterials (WPMN), the Steering Group on Advanced Materials conducted a case study on the potential issues of 2D titanium carbide MXenes. The report describes MXenes as “a group of [two-dimensional (2D)] advanced materials composed of transition metal carbides or...
June 30, 2025

NIA Issues Position Paper on Divergent EU Approaches to Nano and Advanced Materials

On June 11, 2025, the Nanotechnology Industries Association (NIA) published a position paper entitled Bridging the Governance Gap: Divergent EU Approaches to Nano and Advanced Materials that highlights industry challenges with divergent approaches to nano and advanced materials in the European Union (EU). NIA notes that the EU “is at a critical juncture in the approach that it takes towards nano and other advanced materials.” According to NIA, with the European Commission’s (EC)...
May 23, 2025

NASEM Releases Quadrennial Review of NNI, Recommends Renewed and Expanded Infrastructure

On May 20, 2025, the National Academies of Sciences, Engineering, and Medicine (NASEM) announced the release of a report entitled Quadrennial Review of the National Nanotechnology Initiative (2025): Securing U.S. Global Leadership Through Renewed and Expanded Infrastructure. Requested by Congress as part of the 21st Century Nanotechnology Research and Development Act, the report focuses on the infrastructure of the National Nanotechnology Initiative (NNI). The Committee on the Quadrennial Review...
May 14, 2025

Registration Open until May 16, 2025, for Joint Regulatory Risk Assessors Summit on Advancing Safety and Sustainability Assessment of Advanced Materials

On June 19 to June 20, 2025, the European Union (EU) Horizon Europe projects ACCORDs, iCare, MACRAMÉ, and nanoPASS are hosting a joint summit to address the needs of industry and regulators in assessing the safety and sustainability of advanced materials. The summit will feature discussions, latest method developments, and direct engagement with regulators, scientists, and industry professionals. Key sessions will focus on regulatory challenges, scientific developments, and pathways towards...
April 15, 2025

EUON Publishes Nanopinion on Enhancing the Regulatory Application of NAMs to Assess Nanomaterial Risks in the Food and Feed Sector

On April 8, 2025, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “A Qualification System to Accelerate Development and Regulatory Implementation of New Approach Methodologies (NAMs)” by Andrea Haase, Ph.D., German Federal Institute for Risk Assessment (BfR), Shirin M. Usmani, Ph.D., BfR, Irene Cattaneo, European Food Safety Authority (EFSA), Maria Chiara Astuto, EFSA, and Francesco Cubadda, Ph.D., National Institute of Health (ISS). The authors...
April 9, 2025

EC Scientific Committee Begins Public Consultation on Preliminary Opinion on Hydroxyapatite (Nano)

On April 3, 2024, the European Commission’s (EC) Scientific Committee on Consumer Safety (SCCS) began a public consultation on its preliminary opinion on the safety of hydroxyapatite (nano) in oral products. The EC asked SCCS if it considers hydroxyapatite (nano) safe when used in toothpaste up to a maximum concentration of 29.5 percent and in mouthwash up to a maximum concentration of ten percent according to the specifications as reported in the submission, taking into account reasonably...
March 11, 2025

EU Advocate General Recommends Overturning Decision Annulling Harmonized Classification and Labeling of Titanium Dioxide

On February 6, 2025, the European Union (EU) Advocate General (EU AG) recommended that the European Court of Justice (ECJ) overturn the 2022 decision of the General Court annulling the 2019 harmonized classification and labeling of titanium dioxide as a carcinogenic substance by inhalation in certain powder forms. As reported in our December 6, 2022, memorandum, the court annulled the European Commission’s (EC) decision to classify titanium dioxide as a suspected human carcinogen. The French...
February 14, 2025

OECD Tour de Table Includes Information on International Developments Regarding Nanomaterials

The Organisation for Economic Co-operation and Development (OECD) has published the Developments in Delegations on the Safety of Manufactured Nanomaterials and Advanced Materials between July 2023 and June 2024 -- Tour de Table (Tour de Table). Below are highlights on international developments from the Tour de Table: Canada continues with the risk assessments of zinc oxide and titanium dioxide at the nanoscale that are in commerce in Canada, to evaluate their potential for environmental and...
February 7, 2025

OECD Tour de Table Includes Information on U.S. Developments on the Safety of Manufactured Nanomaterials

The Organisation for Economic Co-operation and Development (OECD) has published the Developments in Delegations on the Safety of Manufactured Nanomaterials and Advanced Materials between July 2023 and June 2024 -- Tour de Table (Tour de Table). The Tour de Table lists U.S. developments on the human health and environmental safety of nanomaterials. Risk assessment decisions, including the type of nanomaterials assessed, testing recommended, and outcomes of the assessment include: The U.S....
January 14, 2025

NNCO Releases NNI Supplement to President Biden’s 2025 Budget

On December 19, 2024, the National Nanotechnology Coordination Office (NNCO) released The National Nanotechnology Initiative Supplement to the President’s 2025 Budget, which also serves as the annual report for the National Nanotechnology Initiative (NNI). According to the report, President Biden’s fiscal year (FY) 2025 budget requests over $2.2 billion for NNI, with cumulative funding totaling over $45 billion since the inception of NNI in 2001 when Congress approved increased funding for...
December 31, 2024

NNI Releases 2024 NanoEHS Research Strategy Update

On December 18, 2024, the National Nanotechnology Initiative (NNI) announced the availability of the National Nanotechnology Initiative Environmental, Health, and Safety Research Strategy: 2024 Update. Prepared by the Nanotechnology Environmental and Health Implications (NEHI) Working Group within the Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council, the 2024 update builds on the initial 2011 strategy, laying out a comprehensive,...
December 23, 2024

ECHA Publishes Second Interim Evaluation of EUON

The European Union (EU) Observatory for Nanomaterials (EUON) announced on December 4, 2024, the availability of the European Chemical Agency’s (ECHA) Second interim evaluation of the European Union Observatory for Nanomaterials (EUON). Prepared by WSP acting as a third-party evaluator, the interim evaluation assesses EUON against six criteria: effectiveness; efficiency (including economy and proportionality); relevance; coherence; EU-added value; and utility. WSP’s recommendations include:...
December 16, 2024

EPA Issues Final SNURs for Multi-Walled Carbon Nanotubes (Generic) (P-21-216 and P-21-217)

On December 12, 2024, the U.S. Environmental Protection Agency (EPA) issued several final significant new use rules (SNUR) for certain chemical substances that were the subject of premanufacture notices (PMN) and are also subject to an Order issued by EPA pursuant to the Toxic Substances Control Act (TSCA). 89 Fed. Reg. 100361. Two of the SNURs are for substances identified generically as multi-walled carbon nanotubes (PMN P-21-216 and PMN P-21-217). The SNURs require persons who intend to...
November 12, 2024

EUON Publishes Study on Nanomaterial Applications for Agriculture

The European Union (EU) Observatory for Nanomaterials (EUON) announced on November 12, 2024, that it published a new study evaluating nanomaterials applications in biocidal, plant protection, and fertilizing products used in agriculture. The study, “Collection and review of information on nanomaterial-based and nano-enabled plant protection products, biocidal products and fertilising products,” addresses knowledge gaps on applications, exposure, and hazards of nanomaterials and...
November 4, 2024

EC Committee Issues Final Opinion on New Coating for Titanium Dioxide (Nano Form)

The European Commission’s (EC) Scientific Committee on Consumer Safety (SCCS) published its final opinion on a new coating for titanium dioxide on October 25, 2024. According to the abstract, SCCS concluded that “there are a number of uncertainties and data gaps that do not allow a conclusion on the safety of titanium dioxide (nano) coated with a combination of w/w 6% Aluminium Hydroxide, 14% Sodium Myristoyl Sarcosinate and 10% Dimethicone (Eclipse 70) -- either on the basis of a similarity...
October 24, 2024

Registration Opens for NNI Webinar on Nanometrology Involving Big Data, AI, and Modeling

The National Nanotechnology Coordination Office (NNCO) is organizing a series of National Nanotechnology Initiative (NNI) webinars on nanometrology, metrological challenges, and recent advances in three topical areas: food, agriculture, and the environment; nanoscale medical and pharmaceutical products; and nanoparticles in electronics. Registration is open for the sixth webinar in the series, “Nanometrology for Continuous and Automated Manufacturing.” The November 1, 2024, webinar will...
October 18, 2024

Survey on Carbon-Based Nanomaterials and Analytical Methods Closes November 1, 2024

On October 10, 2024, the European Union (EU) Observatory for Nanomaterials (EUON) announced that, in collaboration with NovaMechanics, it is conducting a survey to gather insights on analytical methods for identifying, characterizing, and quantifying carbon-based nanomaterials in various matrices. According to EUON, the initiative “aims to assess the current situation about analytical methods for these types of nanomaterials, whether advanced or more classical nanomaterials.” Responses will...
October 11, 2024

EFSA Publishes Reports under NAMs4NANO Project

The European Union (EU) Observatory for Nanomaterials (EUON) announced on September 26, 2024, that the European Food Safety Authority (EFSA) has published the following reports under its NAMs4NANO Project: “Review of New Approach Methodologies for Application in Risk Assessment of Nanoparticles in the Food and Feed Sector: Status and Challenges” is a review article on the currently available New Approach Methodologies (NAM) that are potentially useful for risk assessment of nanoparticles in...
October 8, 2024

Canada’s Proposed Plan of Priorities Includes Several Nanoscale Materials; Comments Are Due December 4, 2024

On October 5, 2024, the Minister of the Environment announced in the Canada Gazette publication of a proposed plan of priorities for the assessment of chemical substances. Under the 2023 amendments to the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health are required to “develop, consult on and publish a plan with timelines” by June 2025. The proposed list of prioritized substances for assessment and the rationales for priorities...
September 27, 2024

Final NIOSH Science Post in Series Celebrating NTRC Focuses on Measuring Nanomaterials

On September 25, 2024, the National Institute for Occupational Safety and Health (NIOSH) posted a NIOSH Science Blog item entitled “Celebrating 20 Years of the Nanotechnology Research Center: Measuring the Small Things,” the final installment of the blog series commemorating the 20th anniversary of the Nanotechnology Research Center (NTRC). According to the item, when NTRC was created in 2004, one of its biggest challenges was understanding exactly what to measure and how to measure it....