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On August 10, 2026, the Organisation for Economic Co-operation and Development (OECD) posted a Guidance Document on Toxicokinetics to accommodate Testing of (Nano)particles that provides guidance and considerations around in vivo testing for toxicokinetics of simple-structured, manufactured, poorly soluble, and partially soluble spheroidal particles following oral and inhalation exposure. To reflect that both nano-sized and larger particles are included in the scope of the guidance document,...

The U.S. Environmental Protection Agency (EPA) will hold a two-day training on its high throughput toxicokinetic (HTTK) R package as part of its New Approach Methods (NAM) Training Program: Day 1: Presentation and demo: Wednesday, November 8, 2023, 10 a.m. - 12 p.m. (EST); and Day 2: Expert-led hands-on learning activity: Thursday, November 9, 2023, 10 a.m. - 12 p.m. (EST). According to EPA, toxicokinetics (TK) provides a bridge between toxicity and exposure assessment by...

The U.S. Environmental Protection Agency (EPA) will hold a two-day training on its high throughput toxicokinetic (HTTK) R package as part of its New Approach Methods (NAM) Training Program: Day 1: Presentation and demo: Wednesday, November 8, 2023, 10 a.m. - 12 p.m. (EST); and Day 2: Expert-led hands-on learning activity: Thursday, November 9, 2023, 10 a.m. - 12 p.m. (EST). According to EPA, toxicokinetics (TK) provides a bridge between toxicity and exposure assessment by...

On August 3, 2020, the U.S. Environmental Protection Agency (EPA) announced $3,980,782 in funding to five academic research teams to develop New Approach Methods (NAM) for evaluating chemical toxicokinetics.  According to EPA, compared to traditional animal testing, NAMs allow researchers better to predict potential hazards for risk assessment purposes without the use of traditional methods that rely on animal testing.  EPA is providing a grant of up to $800,000 to each...