Nano and Other Emerging Chemical Technologies Blog

In November 2013, Switzerland’s Federal Office of Public Health (FOPH) updated its precautionary matrix for synthetic nanomaterials, which industry can use to assess nano-specific health and environmental risks of nanoproducts. FOPH states that the precautionary matrix “enables the structured assessment of the ‘nano-specific need for precautions’ when handling synthetic nanomaterials.” FOPH intends the matrix to assist industry with due diligence requirements, and their “duty to...

Japan’s National Institute of Advanced Industrial Science and Technology (AIST) announced in October 2013 a voluntary guidance document on measuring airborne carbon nanotubes (CNT) in workplaces. The Technology Research Association for Single Wall CNTs (TASC), a consortium of nine companies and AIST, prepared the guidance, which is intended to provide a means of CNT safety management.  The guidance summarizes the available practical methods for measuring airborne CNTs:  (1) on-line...

The Air & Waste Management Association (A&WMA) is currently seeking authors, presenters, and panelists for its 107th Annual Conference and Exhibition, which will be held June 24-27, 2014, in Long Beach, California.  The A&WMA Intercommittee Task Force (ITF) on Nanoscale Science and Engineering is sponsoring a track in the technical program that will span a wide array of subjects, including environmental policy, measurement, health effects, monitoring, management, and safety...

On November 8, 2013, the National Institute for Occupational Safety and Health (NIOSH) published a report entitled Current Strategies for Engineering Controls in Nanomaterial Production and Downstream Handling Processes, which identifies and describes strategies for the engineering control of worker exposure during the production or use of engineered nanomaterials. NIOSH notes that there are currently more than 1,000 nanomaterial-containing consumer products available, including “makeup,...

On November 7, 2013, the U.S. Court of Appeals for the Ninth Circuit granted in part and denied in part the Natural Resources Defense Council’s (NRDC) petition for review of the U.S. Environmental Protection Agency’s (EPA) conditional registration of HeiQ AGS-20 and AGS-20 U (collectively, AGS-20) nanosilver products. The court held that “substantial evidence” supported EPA’s decision to use the characteristics of toddlers rather than infants in determining whether AGS-20 placed...

The World Health Organization (WHO) recently published the report of the December 10-11, 2012, WHO expert meeting entitled Nanotechnology and human health: Scientific evidence and risk governance. The conclusion states that while “first generation nanomaterials are being used in a variety of applications and products, they do not seem to present an imminent public health issue.” The conclusion continues, however, and states: “Given the scientific uncertainty and still emerging...

On October 28, 2013, the Wilson Center announced that the updated Nanotechnology Consumer Products Inventory contains 1,628 consumer products that have been introduced to the market since 2005, which is a 24 percent increase since the last update in 2010. The Wilson Center states that the re-launched inventory “seeks to address scientific uncertainty with contributions from those involved with nanomaterials production, use, and analysis.” The Project on Emerging...

The U.S. Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER) posted a blog item on October 24, 2013, concerning the use of nanotechnology to develop new drugs. According to the item, “[t]here are already many products made using materials at the nanoscale, including new kinds of clothing, packaging materials, and light-weight, but strong, building materials.” CDER conducted a series of risk assessment and risk management exercises concerning...

On October 21, 2013, Particle and Fibre Toxicology posted an article entitled “Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology.”  The authors, who are affiliated with the National Institute for Occupational Safety and Health (NIOSH), note that there are currently no known end-point effects in humans following carbon nanotube (CNT) exposure, leading to extrapolation from rodent studies. The purpose of the study was to determine...

On October 8, 2013, Sweden issued a report proposing a national action plan for the safe use and management of nanomaterials. The report’s recommendations, as described in the English summary, include specific actions within several categories. Of particular interest are the following categories and specific recommendations:...

The Product Quality Research Institute (PQRI) will hold a January 14-15, 2014, workshop on “Nanomaterial Drug Products: Current Experience and Management of Potential Risks.” The goals and objectives of the workshop, which is co-sponsored by the United States Pharmacopeia (USP) and American Association of Pharmaceutical Scientists (AAPS) and endorsed by the Society of Toxicology (SOT) are to: The expected outcomes are to establish opportunities for collaboration between...

The Air & Waste Management Association (A&WMA) recently announced the formation of an Intercommittee Task Force (ITF) on Nanoscale Science and Engineering. The ITF will span a wide array of subjects, including environmental policy, measurement, health effects, monitoring, management, and safety issues associated with the development and use of nanomaterials, nanotechnologies, and nanoscale products. Its objectives will likely be: Full participation in the ITF is typically...

On September 3, 2013, the National Industrial Chemicals Notification and Assessment Scheme (NICNAS) posted an electronic copy of its Handbook for Notifiers, which provides guidance for importers and manufacturers of industrial chemicals in Australia. Appendix H includes guidance and requirements for notification of new chemicals that are industrial nanomaterials, and addresses the following topics:...

On September 11, 2013, the European Commission (EC) submitted to the World Trade Organization (WTO) a proposed regulation amending Regulation 1169/2011 concerning the provision of food information to consumers as regards the definition of engineered nanomaterials (ENM). The proposed regulation states that since the regulation refers to ENMs and not nanomaterials in general, natural and incidental nanomaterials should not be included in the definition. The proposed regulation...

On September 20, 2013, the Organization for Economic Cooperation and Development (OECD) announced a recommendation that its Member Countries apply existing regulatory frameworks to manage risks associated with manufactured nanomaterials. The Recommendation, approved on September 19, 2013, expands the scope of the Mutual Acceptance of Data (MAD) in the Assessment of Chemicals to include nanomaterials. Since 2006, OECD has been working to develop approaches for addressing risk...

On September 20, 2013, the National Toxicology Program (NTP) published a Federal Register notice requesting information on 20 substances, mixtures, and exposure circumstances, including nickel nanoparticles, nominated for possible review for future editions of the Report on Carcinogens (RoC). NTP seeks information concerning:  (1) data on current production, use patterns, and human exposure; (2) information about published, ongoing, or planned studies related to evaluating...

The National Nanotechnology Initiative (NNI) has posted a report on its March 2012 international “Symposium on Assessing the Economic Impact of Nanotechnology.” NNI held the symposium in conjunction with the Organization for Economic Cooperation and Development (OECD), and the American Association for the Advancement of Science (AAAS) hosted it. Participants included scientists, engineers, policy analysts, private investors, technology leaders, and the general public from both OECD and...

On September 12, 2013, the National Research Council (NRC) released a report entitled Research Progress on Environmental, Health, and Safety Aspects of Engineered Nanomaterials. The U.S. Environmental Protection Agency (EPA) asked the NRC to perform an independent study to develop and monitor the implementation of an integrated research strategy to address the environmental, health, and safety (EHS) aspects of engineered nanomaterials (ENM). The Committee to Develop a Research...

The Organization for Economic Cooperation and Development (OECD) posted on September 9, 2013, a final report entitled Co-Operation on Risk Assessment: Prioritisation of Important Issues on Risk Assessment of Manufactured Nanomaterials. This document follows on a report published by the Working Party on Manufactured Nanomaterials (WPMN) entitled Important Issues on Risk Assessment of Manufactured Nanomaterials, which identified a range of issues that the WPMN considered important in risk...

The Congressional Research Service (CRS) prepared an August 9, 2013, report entitled The National Nanotechnology Initiative: Overview, Reauthorization, and Appropriations Issues. According to the report, from fiscal year (FY) 2001 through FY 2013, the federal government invested approximately $17.9 billion in nanoscale science, engineering, and technology through the U.S. National Nanotechnology Initiative (NNI). President Obama has requested $1.7 billion in NNI funding for...

The European Commission (EC) Scientific Committee on Consumer Safety (SCCS) announced on September 4, 2013, that it has extended the deadline for comments on the opinion for titanium dioxide (nano form), addendum to the opinion on zinc oxide (nano form), and revision of the opinion on 2,2’-methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) nano form. Comments are due September 18, 2013. The SCCS website states: “Please note that, according to the Rules of...

On August 27, 2013, the U.S. Environmental Protection Agency (EPA) announced its proposed decision to register “Nanosilva,” a nanosilver-containing antimicrobial pesticide product. According to EPA, Nanosilva is a silver-based product “used as a non-food-contact preservative to protect plastics and textiles (e.g., in household items, electronics, sports gear, hospital equipment, bathroom fixtures and accessories) from odor and stain causing bacteria, fungi, mold and mildew.” EPA states...

On August 24, 2013, Canada issued a significant new activity (SNAc) notice for multi-walled carbon nanotubes (MWNCT). The notice states that MWCNTs are not included on the Domestic Substances List and that “a significant new activity in relation to the substance may result in the substance becoming toxic within the meaning of section 64 of the Canadian Environmental Protection Act, 1999.” The notice defines substance as “short tangled multi-walled carbon...

The American National Standards Institute Nanotechnology Standards Panel (ANSI-NSP) will hold a free webinar on October 10, 2013, on its new nanotechnology standards database. ANSI-NSP intends the database to be “a free, comprehensive resource for individuals and groups worldwide seeking information about standards and other relevant documents related to nanomaterials and nanotechnology.” During the webinar, ANSI-NSP will discuss how the database can be used by groups and individuals as...

According to the United Kingdom (UK) Environment Agency Chemical Compliance Team’s annual report, during 2012-2013, the Chemical Compliance Team researched the production and use of nanomaterials by UK industry. On behalf of the Department for Environment, Food and Rural Affairs (Defra), the Chemical Compliance Team surveyed 268 organizations to create a list of who is producing/using nanomaterials in the UK, and to develop an understanding of the types of nanomaterial on sale and in...

On August 9, 2013, Particle and Fibre Toxicology published a study entitled “Extrapulmonary transport of MWCNT following inhalation exposure.” The authors report that inhalation exposure studies of mice were conducted to determine if multi-walled carbon nanotubes (MWCNT) distribute to the tracheobronchial lymphatics, parietal pleura, respiratory musculature, and/or extrapulmonary organs. The study states that tracheobronchial lymph nodes were found to contain 1.08 and 7.34 percent of the...

ACS Nano has published an article entitled “A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment,” which is co-authored by Lynn L. Bergeson. The article presents the results of a January 2013 workshop convened at the California NanoSystems Institute of the University of California, Los Angeles (UCLA) and hosted by the University of California Center for the Environmental Implications of Nanotechnology, as well as the UCLA Center for...

On August 7, 2013, the U.S. Environmental Protection Agency (EPA) promulgated significant new use rules (SNUR) through a direct final rule for 53 chemical substances that were the subject of premanufacture notices (PMN), including two PMN substances whose reported chemical names include the term “carbon nanotube” (CNT). Seven of the chemical substances, including the CNT substances, are subject to consent orders under Section 5(e) of the Toxic Substances Control Act. Persons who intend to...

The National Nanotechnology Initiative (NNI) will hold a September 10-11, 2013, workshop concerning “Stakeholder Perspectives on the Perception, Assessment, and Management of the Potential Risks of Nanotechnology.” NNI is holding the workshop to facilitate stakeholder discussion of key elements needed to assess, manage, and communicate potential risks associated with use of nanomaterials and nanotechnology-enabled products, including: The workshop will include three roundtable...

On July 30, 2013, Particle and Fibre Toxicology published a study entitled “Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes.” In the study, the authors tested the hypothesis that inhalation exposure to multi-walled carbon nanotubes (MWCNT) produces a fibrotic response and that the response is chronically persistent. Male C57BL/6 J mice were exposed in a whole-body inhalation system to a MWCNT aerosol, and the authors examined the fibrotic...

The U.S. International Trade Commission (ITC) published a notice in the July 30, 2013, Federal Register announcing that, following receipt of a letter from the United States Trade Representative (USTR), it instituted investigation No. 332-541, “Trade Barriers that U.S. Small and Medium-Sized Enterprises Perceive as Affecting Exports to the European Union.” According to the notice, USTR’s letter indicated that the U.S., in the Transatlantic Trade and Investment Partnership (TTIP)...

On July 26, 2013, the European Commission’s (EC) Scientific Committee on Consumer Safety (SCCS) posted two documents for comment. The SCCS addendum to its opinion on zinc oxide (nano form) includes the following conclusion: The SCCS opinion on titanium dioxide (nano form) includes the following overall conclusion: 1.  Does SCCS consider that use of titanium dioxide in its nanoform as an UV-filter in cosmetic products in a concentration up to maximum 25.0 % is safe...

The European Commission (EC) called for tenders on June 23, 2013, for a study to assess the impact of possible legislation intended to increase transparency on nanomaterials on the market. The EC states that the objective of the open call for tenders is to assist it “in the preparation of an Impact Assessment to identify and to develop the most adequate means to increase the transparency and to ensure the regulatory oversight for nanomaterials on the market (‘nano-registry’).” The...

On June 19, 2013, the National Institute for Occupational Safety and Health (NIOSH) published a Federal Register notice announcing a public meeting and opportunity for comment on a proposed NIOSH survey. The primary purpose of the survey is to evaluate the use of NIOSH guidelines and risk mitigation practices for safe handling of engineered nanomaterials in the workplace.  The proposed survey will examine the extent to which NIOSH and other guidelines are implemented and the barriers to...

The Nanotechnology Industries Association (NIA) is holding its 2013 NanoImage Competition. NIA invites scientists, photographers, and others to enter. NIA seeks “striking examples that illustrate nanotechnology’s diversity of nature, its range of applications and its unseen beauty.” Submissions will be judged on their originality, technical excellence, composition, overall impact, and artistic merit. The grand prize winner will receive an iPad. The competition is open to all persons...

On December 11, 2013, the U.S. Department of Agriculture (USDA) announced a three-year public-private partnership intended to advance rapidly “the development of the first U.S. commercial facility producing cellulosic nanomaterial, a wood fiber broken down to the nanoscale.” The partnership is between the U.S. Endowment for Forestry and Communities (Endowment) and the U.S. Forest Service. According to USDA, potential applications include ballistic glass replacements, body armor,...

On July 4, 2013, the Belgian Federal Public Service for Health, Food Chain Safety, and Environment notified the European Commission (EC) of a draft decree that would create a register of substances manufactured at the nanoscale based on declarations of products containing such substances by the parties placing these products on the market. Under the draft decree, substances manufactured at the nanoscale, and preparations containing them, would be declared if more than 100 grams of...

On July 4, 2013, the Danish Environmental Protection Agency began a public consultation on a draft order for a nanomaterials register. The draft order would impose annual reporting requirements on manufacturers and importers concerning mixtures and products containing nanomaterials. The reporting requirements would apply to nanomaterials released during use of the product or if the nanomaterial is the reason hazardous substances are released from the product.  The order would take...

On July 3, 2013, the U.S. Environmental Protection Agency (EPA) posted its 2013 Regulatory Agenda, which includes the following item concerning nanoscale materials: Nanoscale Materials; Chemical Substances When Manufactured, Imported, or Processed as Nanoscale Materials; Reporting and Recordkeeping Requirements; Significant New Use Rule: EPA is developing a proposal to establish reporting and recordkeeping requirements under the Toxic Substances Control Act (TSCA) for chemical...

On June 26, 2013, the U.S. Environmental Protection Agency (EPA) promulgated final significant new use rules (SNUR) for 17 chemical substances that were the subject of premanufacture notices (PMN), including for certain carbon nanotubes. The SNURs require persons who intend to manufacture or process any of these 17 chemical substances for an activity that is designated as a significant new use to notify EPA at least 90 days before commencing that activity. The final rule includes EPA’s...

On July 29, 2013, the American National Standards Institute Nanotechnology Standards Panel (ANSI-NSP) announced the launch of a new database compiling information concerning nanotechnology-related standards and affiliated activities.  According to ANSI-NSP, the database is part of a larger effort by ANSI-NSP and its members and partners to increase the visibility of existing and in-development nanomaterials and nanotechnology guidance documents, reference materials, and standards. The...

The National Nanotechnology Initiative (NNI) posted frequently asked questions (FAQ) for small and medium business and industry. According to NNI, the FAQs provide answers to some of the most common questions from the nanotechnology business community. The FAQs provide links to sites where a nanotechnology start-up company can obtain information about government funding opportunities; resources intended to help a small company focusing on research and development of nanotechnology-enabled...

On June 21, 2013, the European Commission (EC) began a consultation on the modification of the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation annexes on nanomaterials. According to the EC, the objective of the initiative is to provide further clarity on how nanomaterials are addressed.  The EC states that REACH must ensure a high level of health, safety, and environmental protection, while also permitting access to innovative products and promoting...

On June 19, 2013, the European Agency for Safety and Health at Work (EU-OSHA) posted a fact sheet entitled “Nanomaterials in Maintenance Work: Occupational Risks and Prevention.” EU-OSHA states that the fact sheet provides a short introduction to nanomaterials and their risks to workers’ safety and health. It explains how workers may encounter nanomaterials when undertaking maintenance work and also presents information on what should be done to prevent exposures....

The Federal Public Service Health, Food Chain Safety, and Environment (FPS), which commissioned a study on the scope of a Belgian national register for nanomaterials and products containing nanomaterials, posted the final report on June 10, 2013. According to the final report, the data collected from individual companies, in addition to market research, has shown that nanomaterials are present on the Belgian market in a large variety of products and along the entire supply chain. The report...

On June 13, 2013, the Organization for Economic Cooperation and Development (OECD) Working Party on Nanotechnology (WPN) published the final report Nanotechnology for Green Innovation. The report summarizes information collected from various projects undertaken by the WPN regarding the use of nanotechnology for green innovation. It also draws on results and conclusions from the March 2012 symposium on “Assessing the Economic Impact of Nanotechnology,” which was organized by the OECD WPN...

On June 11, 2013, the European Parliament adopted a resolution calling for a “new agenda for European consumer policy.” The agenda calls for “adequate consumer protection and product safety in the markets for consumer goods produced using nanotechnology or genetically modified organisms.” The agenda also “[h]ighlights the need for close cooperation between European, national and local authorities and consumer associations in order to establish consultation mechanisms and...

On May 31, 2013, the European Commission (EC) began a public consultation on the new European Union (EU) occupational safety and health policy framework. According to the EC, the main purpose of the consultation is to obtain comments on the results of the evaluation of the European Strategy on Safety and Health at Work 2007-2012.  The EC states that “[t]his should help identify current and future challenges in the occupational safety and health area, and identify solutions...

The European Chemicals Agency (ECHA) began a public consultation on the draft multi-annual work program for 2014-2018. According to the draft work program, ECHA will develop “more refined guidance on the registration of substances in nano-form to provide further detailed advice reflecting the state-of-the-art in regulatory science in this respect and the anticipated adaptation of information requirements for nanomaterials in the [Registration, Evaluation, Authorization and...

The National Nanotechnology Coordination Office (NNCO) will hold a workshop on June 11-12, 2013, to obtain input from stakeholders regarding the goals and objectives of an updated National Nanotechnology Initiative (NNI) Strategic Plan, which is currently under development and scheduled for completion by December 2013. Participants will be invited to suggest additions to and provide feedback on wording and emphasis areas in the NNI goals, the objectives that support these goals, and the...