All Knowledge & Insights By Date

On February 27, 2017, the National Institute for Occupational Safety and Health (NIOSH) announced the availability of a draft chapter to be published in the NIOSH Manual of Analytical Methods entitled “Analysis of Carbon Nanotubes and Nanofibers on Mixed Cellulose Ester Filters by Transmission Electron Microscopy” for public comment.  The draft chapter provides standardized approaches for the analysis of carbon nanoparticles.  NIOSH states that these standardized...

The Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) published a news item on January 16, 2017, entitled “Nanoparticles — to handle with care.”  IRSST states that although research is still in development, it appears that nanoparticles can enter the respiratory tract or penetrate through the skin and make their way to the bloodstream, which may carry the nanoparticles to various organs.  While studies have been...

The Organization for Economic Cooperation and Development (OECD) published a report entitled Alternative Testing Strategies in Risk Assessment of Manufactured Nanomaterials:  Current State of Knowledge and Research Needs to Advance Their Use.  Experts from academia, industry, public interest groups, and government researched, analyzed, and discussed how alternative models could be used to advance the risk analysis of manufactured nanomaterials.  The objectives were to...

On January 19, 2017, the U.S. Environmental Protection Agency (EPA), together with a host of other federal agencies, announced revisions via a final rule to modernize, strengthen, and make more effective the Federal Policy for the Protection of Human Subjects that was originally promulgated as a Common Rule in 1991.  82 Fed. Reg. 7151.  The Federal Register publication states that this final rule is intended to “better protect human subjects involved in research,...

On December 29, 2016, the U.S. Environmental Protection Agency (EPA) issued a notice regarding the availability of final test guidelines, OCSPP Series 850 Group A -- Ecological Effects, part of a series of test guidelines established by the Office of Chemical Safety and Pollution Prevention (OCSPP) for use in testing pesticides and chemical substances to develop data for submission to EPA under the Federal Food, Drug and Cosmetic Act (FFDCA), the Federal Insecticide, Fungicide and...

On December 20, 2016, the U.S. Environmental Protection Agency (EPA) announced the start of a pilot program to evaluate the usefulness and acceptability of a mathematical tool (the GHS Mixtures Equation), which is used in the Globally Harmonized System of Classification and Labeling of Chemicals (GHS).  EPA states that the goal of the pilot program is to “evaluate the utility and acceptability of the GHS Mixtures Equation as an alternative to animal oral and inhalation toxicity...

The Occupational Safety and Health Administration (OSHA) released on December 20, 2016, a white paper entitled Sustainability in the Workplace:  A New Approach for Advancing Worker Safety and Health.  The paper highlights the importance of including worker safety and health in the growing movement toward sustainability and corporate responsibility.  According to the paper, research on sustainability does not include occupational safety and health.  The paper notes that...

On November 14, 2016, the U.S. Department of Agriculture (USDA) and its partners celebrated the successful journey of the first commercial flight powered in part by a new renewable fuel made from wood waste. The demonstration flight, operated by Alaska Airlines, was made possible due to a five-year $39.6 million research project to develop a viable renewable fuel source from cellulose-rich wood harvest leftovers funded by USDA’s National Institute of Food and Agriculture and led by...

On November 1, 2016, the Biotechnology Innovation Organization (BIO) issued a call for panel session proposals for the 2017 World Congress on Industrial Biotechnology.  Leaders from biotechnology, bioenergy, chemical, consumer products manufacturing, and agricultural industries as well as academia and financial sectors industries are invited to submit proposals to present on groundbreaking research and partnerships in the industrial biobased industry.  Specific program tracks for the ...

The International Organization for Standardization (ISO) recently published ISO/TR 18196:2016, “Nanotechnologies — Measurement technique matrix for the characterization of nano-objects.”  The document provides a matrix intended to guide users to commercially available techniques relevant to the measurements of common physiochemical parameters for nano-objects.  Some techniques are also applicable to nanostructured materials.  As scientific advances are made and additional...

On November 1, 2016, the U.S. Environmental Protection Agency (EPA) Office of Research and Development (ORD) announced a meeting of the Board of Scientific Counselors’ (BOSC) Chemical Safety for Sustainability Subcommittee meeting via notice in the Federal Register.  This meeting will be held at the U.S. Environmental Protection Agency’s (EPA) Main Campus Facility in North Carolina, and will be open to the public.  Those interested in attending must register online by...

The International Organization for Standardization (ISO) published ISO/TR 16196:2016, “Nanotechnologies — Compilation and description of sample preparation and dosing methods for engineered and manufactured nanomaterials.”  The goal of the standard is to assist scientists and experts to understand, plan, choose, and address issues relevant to nanomaterials before and during toxicological testing.  The descriptions of sample preparation method factors for both in vitro and in...

On September 19, 2016, the U.S. Environmental Protection Agency’s (EPA) Office of Inspector General (OIG) issued a report, EPA Needs a Risk-Based Strategy to Assure Continued Effectiveness of Hospital-Level Disinfectants, the result of OIG’s review of EPA’s Antimicrobial Testing Program (ATP) to “determine whether the program ensures the efficacy of EPA-registered hospital sterilants, disinfectants, and tuberculocides (“hospital-level disinfectants”); and to evaluate options for...

The threat of the Zika Virus grows every day, and the need for clear information is especially pressing if you are pregnant.  How do you prevent getting infected with the Zika Virus, and what insect repellents are best?  The first question is easy to answer:  public health experts agree that women who are pregnant or who might be pregnant should use insect repellents.  The answer to the second question is not so simple. I am a former senior official at the U.S. Environmental...

The European Food Safety Authority (EFSA) requested a review of the already marketed and in-development applications of nanomaterials in the agri/feed/food sectors.  The results of the review are published in the August 2016 issue of Trends in Food Science & Technology in an article entitled “Nanomaterials for products and application in agriculture, feed and food.”  The article highlights include: Nanotechnology is applied in agricultural production, animal feed,...

The Organization for Economic Cooperation and Development (OECD) recently published several dossier summaries for nanomaterials tested as part of its Testing Program of Manufactured Nanomaterials.  Under the Program, sponsors tested 11 nanomaterials for:  nanomaterial information/identification; physical-chemical properties and material characterization; environmental fate; toxicological and eco-toxicological effects; environmental toxicology; mammalian toxicology; and material...

On June 28, 2016, Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) issued a press release announcing the availability of a study on “Efficiency Evaluation of N95 FFRs under Cyclic and Constant Flows.”  Researchers tested the efficacy of N95 filtering facepiece respirators (FFR) in conditions of constant and cyclical air flow, simulating human breathing, from 42 to 360 liters per minute.  According to the press release, N95 respirators “are the personal...

On June 15, 2016, the National Institute for Occupational Safety and Health (NIOSH) posted a number of Program Performance One-Pagers (PPOP), including a May 2016 PPOP on the NIOSH Nanotechnology Research Center (NTRC).  The PPOP states that the NTRC focuses on increasing understanding of hazards and related health risks to workers who make and use nanomaterials and preventing occupational exposures to nanomaterials.  The PPOP includes the following future NIOSH actions:...

The May 2016 issue of NIOSH Research Rounds includes an item entitled “Research Explores Workplace Exposure to Carbon Nanotubes.”  The National Institute for Occupational Safety and Health (NIOSH) summarizes the following two published papers by NIOSH investigators with partners at Kazan State Medical University, in Kazan, Russia, that explore whether workplace exposure to multi-walled carbon nanotubes could pose a risk for lung disease.  For both studies, participants...

On April 19, 2016, the European Union (EU) NanoSafety Cluster announced the availability of the “Closer to the Market” Roadmap (CTTM).  The NanoSafety Cluster states that the CTTM is a “multi-dimensional, stepwise plan targeting a framework to deliver safe nano-enabled products to the market.”  The steps include:  (1) building an inclusive collaboration network; (2) bringing together scientific and entrepreneurial experts; (3) strengthening dialog of all stakeholders to raise...

The Organization for Economic Cooperation and Development recently posted a March 29, 2016, report entitled Developments in Delegations on the Safety of Manufactured Nanomaterials — Tour de Table.  The report compiles information, provided by Working Party on Manufactured Nanomaterials (WPMN) participating delegations, before and after the November 2015 WPMN meeting, on current developments on the safety of manufactured nanomaterials.  OECD intends the report to provide delegations with...

On March 31, 2016, the National Nanotechnology Initiative (NNI) published its supplement to the President’s 2017 budget request.  The supplement also serves as the NNI annual report called for under the provisions of the 21st Century Nanotechnology Research and Development Act of 2003.  NNI states that the President’s budget request provides $1.4 billion for NNI, with a cumulative total of nearly $24 billion since the inception of NNI in 2001 (including the 2017 request), “affirming...

On March 28, 2016, the National Nanotechnology Coordination Office (NNCO) announced the release of a report entitled Quantifying Exposure to Engineered Nanomaterials (QEEN) from Manufactured Products:  Addressing Environmental, Health, and Safety Implications.  The report summarizes the July 7-8, 2015, QEEN workshop, which was sponsored by the Consumer Product Safety Commission (CPSC) and co-hosted by the National Nanotechnology Initiative (NNI).  The main goals for...

The National Nanotechnology Initiative (NNI) issued a March 23, 2016, press release concerning the launch of a Nanotechnology Signature Initiative (NSI), Water Sustainability through Nanotechnology:  Nanoscale Solutions for a Global-Scale Challenge.  The Office of Science and Technology posted a blog item on March 23, 2016, concerning the new NSI, stating that it is intended “to take advantage of the unique properties of engineered nanomaterials to generate...

On March 8, 2016, the U.S. Environmental Protection Agency (EPA) published a notice in the Federal Register stating that the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Scientific Advisory Panel (SAP) will hold a three-day meeting scheduled for April 19-21, 2016, from 9:00 a.m. to 5:00 p.m. (EDT) to consider and review Chlorpyrifos:  Analysis of Biomonitoring Data.  The meeting will be held at EPA’s Conference Center, Lobby Level, One...

The Organization for Economic Cooperation and Development (OECD) recently published the following reports: Physical-chemical properties of nanomaterials: Evaluation of methods applied in the OECD-WPMN testing programme: The Netherlands volunteered to lead an initial detailed evaluation of the applicability of the test methods applied to determine the physico-chemical properties of different types of nanomaterials in the Testing Program.  The evaluated dossiers include information on...

On February 16, 2016, the Danish Environmental Protection Agency (Danish EPA) posted a report entitled Assessment of Nano-enabled Technologies in Cosmetics.  The report reviews the available literature on nano-enabled technologies for cosmetic products, specifically addressing soluble nano-transporters.  Accompanying the report is an appraised database summarizing the literature that formed the basis of the review.  The database addresses the following areas:  types and...

According to a February 22, 2016, press release from the Organization for Economic Cooperation and Development (OECD), an OECD report states that “[u]rgent research is needed to assess the possible risks to human health and ecosystems from the ever-increasing amounts of engineered nanomaterials going into household waste and ending up in the environment.”  The OECD report, Nanomaterials in Waste Streams:  Current Knowledge on Risks and Impacts, states that engineered...

The Organization for Economic Cooperation and Development (OECD) has posted the following reports concerning nanomaterials: Considerations for Using Dissolution as a Function of Surface Chemistry to Evaluate Environmental Behaviour Of Nanomaterials in Risk Assessments:  A Preliminary Case Study Using Silver Nanoparticles — The December 18, 2015, report discusses preliminary findings on dissolution by media type, provides recommendations, compares silver nanoparticles to other...

The European Food Safety Authority (EFSA) published on January 11, 2016, the Scientific Network for Risk Assessment of Nanotechnologies in Food and Feed (Nano Network) annual report for 2015.  The report states that, during 2015, the Nano Network followed-up on its four priority topics:  (1) the need for an inventory of nanomaterials in products on the market; (2) the analysis and monitoring of products under development and on the market; (3) the need for suitable measuring...

In December 2015, the proceedings from the March 12-13, 2015, U.S.-European Union (EU) joint workshop on “Bridging NanoEHS Research Efforts” were posted online.  The workshop was sponsored by the European Commission (EC) and the National Nanotechnology Initiative (NNI).  It brought together European and American scientists engaged in nanotechnology environmental, health, and safety (nanoEHS) research to identify areas of shared nanoEHS interest and mechanisms for...

Registration is open for the National Nanotechnology Initiative’s (NNI) December 11, 2015, webinar entitled “All Hands on Deck for Improving Data Quality.”  The one-hour webinar will include a presentation from Dr. Paul Weiss, Distinguished Professor at UCLA and Editor-in-Chief of ACS Nano, on nanotechnology data reproducibility challenges and needs.  Dr. Ewan Birney, Director of European Bioiformatics Institute, will present a case study on the formation of the...

The Organization for Economic Cooperation and Development (OECD) recently posted four reflection papers that discuss the possible release of nanomaterials from waste treatment operations and a literature review on four specific waste treatment processes of recycling, incineration, landfilling, and wastewater treatment.  The papers aim to point out the knowledge gaps and areas where further research is needed. Incineration of Waste Containing Nanomaterials: The paper was developed to attempt...

On November 10, 2015, the Danish Environmental Protection Agency posted the following publications concerning nanomaterials: Environmental assessment of nanomaterial use in Denmark: This is the concluding report of the project “Nanomaterials — occurrence and effects in the Danish environment” (NanoDEN). The projects in NanoDEN aimed to investigate and generate new environmentally relevant knowledge concerning nanomaterials on the Danish market and to assess the possible associated risks to...

On October 20, 2015, the White House announced a grand challenge to develop transformational computing capabilities by combining innovations in multiple scientific disciplines.  The Office of Science and Technology Policy (OSTP) states that, after considering over 100 responses to its June 17, 2015, request for information, it “is excited to announce the following grand challenge that addresses three Administration priorities — the National Nanotechnology Initiative,...

The Organization for Economic Cooperation and Development (OECD) posted a new publication in its Series on the Safety of Manufactured Nanomaterials, Preliminary Guidance Notes on Nanomaterials: Interspecies Variability Factors in Human Health Risk Assessment. The report includes the following recommendations for further work: The Expert Opinion prepared in support of the project noted a general lack of availability of data from repeated-dose toxicity studies in different species. In...

The U.S. Environmental Protection Agency (EPA) posted on September 30, 2013, a final report entitled Comprehensive Environmental Assessment Applied to Multiwalled Carbon Nanotube Flame-Retardant Coatings in Upholstery Textiles: A Case Study Presenting Priority Research Gaps for Future Risk Assessments. The final report presents a case study of multiwalled carbon nanotubes (MWCNT) used in flame-retardant coatings applied to upholstery textiles. EPA states that the case study is organized...

The National Nanotechnology Initiative (NNI) announced on September 17, 2015, that the National Science Foundation (NSF) will provide a total of $81 million over five years to support 16 sites and a coordinating office as part of a new National Nanotechnology Coordinated Infrastructure (NNCI).  The awards are for up to five years and range from $500,000 to $1.6 million each per year.  Nine of the sites have at least one regional partner institution.  The 16 sites are...

On September 16, 2015, the Woodrow Wilson International Center for Scholars (Wilson Center) released a funding report on U.S. Trends in Synthetic Biology Research Funding. The Wilson Center found that the U.S. invested approximately $820 million in synthetic biology research between 2008 and 2014, with nearly 60 percent of the funding coming from the Defense Advanced Research Projects Agency (DARPA). The National Science Foundation (NSF) has also been funding synthetic biology research,...

In an opinion issued on September 10, 2015, the U.S. Court of Appeals for the Ninth Circuit vacated the U.S. Environmental Protection Agency’s (EPA) unconditional registration for the pesticide sulfoxaflor and remanded the matter to EPA to obtain further studies and data regarding the effects of sulfoxaflor on bees and bee colonies.  Sulfoxaflor is a new insecticide in the class of insecticides referred to as neonicotinoids, but its mechanism of action is distinct from other...

The Federal Public Service (FPS) Health, Food Chain Safety and Environment, the FPS Employment, Labor and Social Dialogue, and the FPS Economy, Small and Medium-sized Enterprises (SME), Self-Employed and Energy will hold a workshop on “Nano in Belgium” on October 22, 2015.  The workshop will focus on nano research, and the agencies encourage representatives from Belgian research institutes, universities, and industries to participate by either posters or oral presentation.  The main goal...

On Tuesday, August 25, 2015, in a Federal Register notice, the U.S. Environmental Protection Agency (EPA) announced the addition of three Office of Chemical Safety and Pollution Prevention (OCSPP) final test guidelines to its 890 Series, entitled “Endocrine Disruptor Screening Program Test Guidelines,” as follows: Medaka Extended One Generation Reproduction Test (MEOGRT), OCSPP Test Guideline 890.2200; Larval Amphibian Growth and Development Assay (LAGDA), OCSPP Test...

On August 4, 2015, the U.S. Environmental Protection Agency (EPA) announced the availability of its Final 2014 Effluent Guidelines Program Plan.  The Final Program Plan includes the following findings from EPA’s review of engineered nanomaterials in industrial wastewater: Some manufacturing and processing methods likely generate wastewater, but the quantity generated and waste management practices are not documented; Toxicity hazards from engineered nanomaterials have been...

The release of the first Tier 1 assessments in the Endocrine Disruptor Screening Program (EDSP) by the U.S. Environmental Protection Agency (EPA) on June 30, 2015, is a significant bench-mark in the program since the original List 1 test orders were initially issued in October 2009.  Fifteen of the original 67 List 1 chemicals were subsequently cancelled or discontinued by the respective pesticide registrants.  The intended purpose of the Tier 1 screening was to identify...

On June 19, 2015, the U.S. Environmental Protection Agency (EPA) announced a plan for incorporating validated high throughput assays and a computational model into the Endocrine Disruptor Screening Program (EDSP) to screen chemicals for their ability to interact with the endocrine system.  These proposed new methods would serve as an alternative for three of the eleven current assays in the EDSP Tier 1 screening battery, specifically the estrogen receptor binding (ER), estrogen...

Taking Nanotechnological Remediation Processes from Lab Scale to End User Applications for the Restoration of a Clean Environment (NanoRem) is a research project funded through the European Commission (EC) FP7. On May 6, 2015, NanoRem issued a press release announcing that no significant toxicological effects were found on soil or water organisms when ecotoxicological tests were undertaken for a range of nanoparticles that could be used for remediation projects: NanoFer 25S, made from...

On June 17, 2015, the Environmental Protection Agency (EPA) published a notice announcing the availability for comment of three draft revised 810 series test guidelines developed by the Office of Chemical Safety and Pollution Prevention (OCSPP).  These test guidelines will provide updated guidance on antimicrobial efficacy testing to the regulated community. EPA states that when these guidelines were published in final in 2012, they drew criticism as confusing and inaccurate.  EPA...

The Organization for Economic Cooperation and Development (OECD) issued a June 9, 2015, press release entitled “OECD chemical studies show way forward for nanomaterial safety.”  The press release states: Today the OECD marked the end of a seven-year experimental testing program, investigating 11 commercially viable nanomaterials across over 110 different chemical tests; The results were coordinated from across 11 countries with tests and data generated from dozens of government...

The Consumer Product Safety Commission (CPSC) is sponsoring a July 7-8, 2015, workshop, co-sponsored by the National Nanotechnology Initiative (NNI), entitled “Quantifying Exposure to Engineered Nanomaterials from Manufactured Products — Addressing Environmental, Health, and Safety Implications.” This is a technical workshop to determine the state of the science and the tools and methods available to characterize and quantify exposure to engineered nanomaterials from consumer products....

On April 27, 2015, the National Institute for Occupational Safety and Health (NIOSH) announced publication of “Carbon Nanotube and Nanofiber Exposure Assessments: An Analysis of 14 Site Visits” in Annals of Occupational Hygiene.  The paper is the second report from NIOSH’s Industrywide Study.  According to NIOSH, the findings illustrate which tasks have the highest exposures, trends in exposure, nature and character of materials involved, effectiveness of controls when used,...