All Knowledge & Insights By Date

On April 8, 2025, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “A Qualification System to Accelerate Development and Regulatory Implementation of New Approach Methodologies (NAMs)” by Andrea Haase, Ph.D., German Federal Institute for Risk Assessment (BfR), Shirin M. Usmani, Ph.D., BfR, Irene Cattaneo, European Food Safety Authority (EFSA), Maria Chiara Astuto, EFSA, and Francesco Cubadda, Ph.D., National Institute of Health (ISS). The authors...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on December 4, 2024, the availability of the European Chemical Agency’s (ECHA) Second interim evaluation of the European Union Observatory for Nanomaterials (EUON). Prepared by WSP acting as a third-party evaluator, the interim evaluation assesses EUON against six criteria: effectiveness; efficiency (including economy and proportionality); relevance; coherence; EU-added value; and utility. WSP’s recommendations include:...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on November 12, 2024, that it published a new study evaluating nanomaterials applications in biocidal, plant protection, and fertilizing products used in agriculture. The study, “Collection and review of information on nanomaterial-based and nano-enabled plant protection products, biocidal products and fertilising products,” addresses knowledge gaps on applications, exposure, and hazards of nanomaterials and...

On October 10, 2024, the European Union (EU) Observatory for Nanomaterials (EUON) announced that, in collaboration with NovaMechanics, it is conducting a survey to gather insights on analytical methods for identifying, characterizing, and quantifying carbon-based nanomaterials in various matrices. According to EUON, the initiative “aims to assess the current situation about analytical methods for these types of nanomaterials, whether advanced or more classical nanomaterials.” Responses will...

The European Chemicals Agency (ECHA) is evaluating the function of the European Union (EU) Observatory for Nanomaterials (EUON). As part of its evaluation, ECHA is conducting a survey to collect responses from EUON website visitors and stakeholders. The survey includes questions concerning evaluation criteria such as use, effectiveness, coherence, EU-added value, and utility. The survey notes that under an ongoing legislative proposal, the European Commission (EC) foresees setting up a common...

The European Union (EU) Observatory for Nanomaterials (EUON) invites proposals for upcoming studies aimed at addressing knowledge gaps for nanomaterials within the EU market, such as: EUON notes that studies are based on desk research and surveys and should not require laboratory research. EUON states that studies can cover nanomaterials in general, a specific nanomaterial, or a defined group of nanomaterials. EUON will make the outcome and study reports available on its website. Proposals are...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on February 5, 2024, that the European Chemicals Agency (ECHA) has published two new ex-ante publicity notices for two service contracts:...

The European Chemicals Agency (ECHA) has commissioned, as part of the activities of the European Union (EU) Observatory for Nanomaterials (EUON), a study on the collection and review of information on nanomaterial-based and nano-enabled plant protection products, biocidal products, and fertilizing products. The study includes a systematic literature and documentary review on nanoforms of (active) substances and delivery systems of the corresponding formulations used in biocidal products, plant...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on October 10, 2023, that it published “A study on valid in silico modelling tools and read-across approaches, including creation of case studies on read-across for specific (types of) nanomaterials” that analyzes read-across and in silico approaches as alternative methods to conventional hazard and risk assessments for nanomaterials. According to EUON, the study identifies 190 alternative models and methodologies for...

On August 2, 2023, the European Union (EU) Observatory for Nanomaterials (EUON) announced that it published a study that systematically reviews and assesses alternative methods for the testing of the safety of nanomaterials without the use of animals. According to EUON, the main aim of the study was to collect and provide accurate and transparent information on new approach methodologies (NAM) available for the human safety assessment of nanomaterials and to create a comprehensive...

The European Union (EU) Observatory for Nanomaterials (EUON) has posted two Nanopinions:...

The European Union (EU) Observatory for Nanomaterials (EUON) has issued a call for study proposals. EUON is looking for studies on: According to EUON, the scope of the study can be on nanomaterials in general, a specific nanomaterial, or a defined group of nanomaterials. EUON will assess all proposals, and if selected, they will be carried out through EUON’s existing procurement channels. EUON will post the outcome and study reports on its website. EUON states that...

On January 17, 2023, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “EU 2025: Enjoying the Benefits of Nanotechnology and NMS” by Dr. Anastasios Papadiamantis and Dr. Antreas Afantitis, both of NovaMechanics Ltd. The authors report the findings of a study commissioned by EUON on the EU market for nanomaterials, including substances, uses, volumes, and key operators. The authors state that the EU (including the European Economic Area (EEA)...

On December 20, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Controlling Exposure to Nanomaterials” by Dr Araceli Sánchez, Spanish Institute of Health and Safety (INSST). Sánchez notes that over the last 15 years, scientists have paid attention to the development of new instruments capable of measuring personal exposure to nanosize particles, and new frameworks, methodologies, and standards to assess and control exposure to engineered...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on December 12, 2022, the results of a desk study entitled Study on (bio)degradation, persistence and safe by design of nanomaterials. The study aimed at providing information on the state of the art, the existing gaps, and the research needs for the (bio)degradation and persistence of nanomaterials and their relevant organic coatings. Another objective was to examine the current state of the art for safe by design (SbD)...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on December 7, 2022, publication of a June 2022 report by the European Chemicals Agency (ECHA) entitled Assessment of the potential impact of graphene, graphene oxide and other 2D materials on health, and the environment. Commissioned by EUON, the report provides a systematic review and critical assessment of the health and environmental effects of graphene, graphene oxide, and other two-dimensional (2D)...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on November 7, 2022, that it published a study on the EU market for nanomaterials, including substances, uses, volumes, and key producers, traders, and users. The study also covers the European Economic Area (EEA) countries and Switzerland. EUON states that according to the study, which was carried out in 2021 as a combination of literature research, surveys, and interviews, the European nanomaterial market is...

On September 13, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Can the Brain’s Gatekeeper Fight a Nano-Attack?” by Dr. Eugenia (Éva) Valsami-Jones, Professor of Environmental Nanoscience at the University of Birmingham, who co-authored an article entitled “Biotransformation modulates the penetration of metallic nanomaterials across an artificial blood–brain barrier model.” The researchers set out to explore systematically how...

On June 28, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Models to Characterize Exposures to Manufactured Nanomaterials in OECD” by Vladimir Murashov, Ph.D., Senior Scientist in the Office of the Director, National Institute for Occupational Safety and Health (NIOSH), and John Howard, M.D., Director of NIOSH and Administrator of the World Trade Center Health Program in the U.S. Department of Health and Human Services. The authors...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on June 17, 2022, that it is looking for topics that could be addressed in its upcoming studies. EUON conducts up to three studies annually to address knowledge gaps on nanomaterials. EUON is looking for study topics that address: EUON states that the scope of the study can be on nanomaterials in general, a specific nanomaterial, or a defined group of nanomaterials. Studies are run for three to...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on June 10, 2022, that NanoData has been updated with “a new look and feel to improve the user experience.” NanoData is the knowledge base on nanosciences and -technology hosted by EUON. It contains data on different products, research projects, publications, patents, and organizations. According to EUON, users can now visualize statistics through built-in charts and graphs. The data can be easily...

On May 31, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Urinary MicroRNA-based Early Cancer Detection Using Nanowire-based Devices” by Dr. Yasui Takao on using nanowire devices to extract microRNAs (miRNA) from urine to distinguish cancer patients from healthy individuals and improve the early detection of cancer. According to Yasui, researchers designed a device equipped with 100 million zinc oxide nanowires that can extract a...

The European Union (EU) Observatory for Nanomaterials (EUON) has launched two calls for tenders to conduct studies on nanomaterials. The first call for tender is on valid in silico modeling tools and read-across approaches, including creating case studies on read-across for specific types of nanomaterials. According to the call for tender, the study proposes to examine the use of these tools for nanomaterials and to draw potential conclusions (for both regulators and industry/small-...

On February 24, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Are nanoplastics hazardous? The way forward to overcome the uncertainties of risk assessment” by Dr. Anita Jemec Kokalj and Dr. Dana Kühnel about defining the criteria to evaluate which properties of nanoplastics should be reported in future studies to decrease uncertainties in their risk assessment. The authors state that nanoplastics “are complex environmental pollutants...

On January 18, 2022, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “What does ‘Graphene’ really look like and why is it not ‘carbon nanotubes’” by Dr. Alberto Bianco, Dr. Maurizio Prato, and Dr. Kostas Kostarelos, of the Graphene Flagship, an EU research initiative, about graphene and why it is not the same as carbon nanotubes. The article states that in particular, the authors wish to emphasize “that ‘graphene’ as a...

On December 21, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “ACEnano: Goodbye, Hello” by Dr. Eugenia Valsami-Jones about Project ACEnano, a Horizon2020 project that recently completed its 4.5-year course. The project’s main goal was to strengthen clarity into nanomaterial risk assessment using a tiered approach to the physicochemical characterization of nanomaterials. Valsami-Jones describes the analytical solutions produced by...

On November 15, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) announced the release of a report that it commissioned entitled “Study on the Product Lifecycles, Waste Recycling and the Circular Economy for Nanomaterials.” The study updates and expands on the 2016 Organization for Economic Cooperation and Development (OECD) document entitled “Nanomaterials in Waste Streams — Current Knowledge on Risks and Impacts.” The report covers waste streams containing...

On July 15, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “The ECHA Nanomaterials Expert Group (NMEG)” by Frank Le Curieux, Scientific Area Leader for Genotoxicity at the European Chemicals Agency (ECHA). Le Curieux provides a brief summary of the creation of NMEG and its history. NMEG’s current mandate is to provide informal and non-binding scientific and technical advice on questions related to nanomaterials or nanoforms of substances...

The European Chemicals Agency (ECHA) has launched a call for tenders to perform a study “Assessment of the potential impact of graphene, graphene oxide and other 2D materials on health, and the environment” as part of the European Union (EU) Observatory for Nanomaterials (EUON). According to the description, the goal of the study is to conduct a systematic literature review of the health and environmental effects of graphene, graphene oxide, and other two-dimensional (2D) materials,...

On June 26, 2019, the Council of the European Union (EU) announced that it adopted conclusions on chemicals intended to “offer political guidance on the development of a sustainable EU chemicals policy strategy.”  The June 26, 2019, press release notes that the conclusions address in particular the topics of Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation, endocrine disruptors, nanomaterials, and pharmaceuticals.  According to the...

On May 31, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Updating our language: why we should not paint all nanoforms with the same brush” by Chiara Venturini, Director General of the Nanotechnology Industries Association (NIA). Venturini reviews how the EU’s language has evolved. In 2011, the European Commission (EC) adopted a definition that describes a nanomaterial as a material at the nanoscale. In 2020, the EC amended Annex II...

The European Chemicals Agency (ECHA), as part of the activities of the European Union (EU) Observatory for Nanomaterials (EUON), is conducting a stakeholder survey on the substances available as nanomaterials in the EU market. The survey includes a market study of the nanomaterials, including substances, uses, volumes, and key operators in the EU. According to EUON’s May 21, 2021, news item, the survey aims to provide an overview of the substances that are available as...

On April 29, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Biotransformation of nanomaterials while transferring in the food chain” by Dr. Fazel A. Monikh.  As the application of nanomaterials increases, more of these materials are released in the environment.  Monikh states that some nanomaterials that are persistent in the environment raise concerns as they can enter organisms’ bodies, accumulate in their organs, and...

On March 19, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “ECETOC task force ensures society benefits from safe nanomaterials via efficient safety assessments that require minimal animal testing” by authors from BASF and the Center for Chemical Safety Assessment (ECETOC).  The column reviews ways to assess the safety of nanomaterials while minimizing animal testing.  According to the authors, the NanoApp developed by the ECETOC...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on March 19, 2021, that it is looking for topic suggestions that could be addressed in its upcoming studies.  According to EUON, up to three studies are conducted annually to address knowledge gaps on nanomaterials that are of interest to the general public and the research community.  EUON states that it seeks studies that address: The scope of the study can be on nanomaterials in general, a specific...

On February 19, 2021, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “eREACHNano helps you to register nanoforms under REACH” by Dorte Rasmussen, Ph.D., who has been working on the exposure and risk assessment of chemicals at DHI A/S for almost 25 years.  Rasmussen describes eREACHNano, a tool developed to explain Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation requirements for nanoforms. ...

The Organization for Economic Cooperation and Development (OECD) has published the latest edition of the Developments in Delegations on the Safety of Manufactured Nanomaterials — Tour de Table.  The Tour de Table compiles information provided by delegations on the occasion of the 20th meeting of the OECD Working Party on Manufactured Nanomaterials (WPMN) in September 2020.  Below are highlights from the Tour de Table: Between November 2018 and August 2020, EPA...

In December 2020, the European Commission (EC) Directorate-General (DG) for Research and Innovation opened a call for tenders for “Providing market data about nanotechnology to enhance transparency.”  The description states that the study on nanotechnology/nanomaterials is aimed to provide a new set of data from the period of 2017 to 2020 into the NanoData database, available on the European Union (EU) Observatory for Nanomaterials (EUON) website.  This study will follow up on...

The European Union (EU) Observatory for Nanomaterials (EUON) is conducting a web satisfaction survey.  EUON provides information on the safety, innovation, research, and uses of nanomaterials on the EU market.  It is intended for stakeholders developing policies in the area, consumers, industry representatives, and non-governmental organizations.  EUON is funded by the European Commission (EC) and hosted and maintained by the European Chemicals Agency (ECHA).  Information from the survey...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on November 16, 2020, the results of a study on how citizens perceive nanomaterials and their potential risks to human health and the environment.  According to EUON, the study found that general awareness about the nature, characteristics, and properties of nanomaterials is low.  EUON notes that the level of awareness has increased compared to earlier surveys, however, and is expected to continue...

On August 31, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Nanosilver in healthcare — does the silver bullet exist?” by Dr. Dorota Napierska, Chemicals Policy and Projects Officer, Health Care Without Harm Europe (HCWH Europe).  Napierska examines how beneficial the properties of nanosilver are in clinical settings and the risks involved.  Napierska notes that a key point in assessing the toxicity of nanosilver is to adopt...

On July 23, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Material manufacturing from nano-scaled particles:  moving forward using plants” by Dr. Blaise Tardy, Research Fellow, Bio-Based Colloids and Materials Research Group — Aalto University in Finland.  Dr. Tardy notes that bio-based nanomaterials such as nanocellulose “have shown great promise in forming high performance materials, with the potential to replace...

On July 1, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Polymer based nanocomposites – enabling innovation, resource efficiency and helping to fight climate change” by Dr. Sabine Lindner, Consumer and Environmental Affairs, PlasticsEurope Deutschland e.V.  Dr. Lindner notes how the addition of nanoscale particles to plastic matrices can improve the properties of products such as plastic packaging for food.  According to Dr....

The European Union (EU) Observatory for Nanomaterials (EUON) posted a Nanopinion on June 12, 2020, entitled “Pigments:  The oldest nanomaterials in human history facing modern day challenges.”  Dr. Heike Liewald, Managing Director, Eurocolour e.V., and Giuliana Beck, Advisor, German association of producers of pigments and fillers, describe how the introduction of nano-specific requirements in statutes has significantly increased the regulatory burden.  The authors state that...

The European Union (EU) Observatory for Nanomaterials (EUON) announced on May 20, 2020, that a recent study has analyzed existing research on whether nanomaterials used in consumer products and at workplaces are absorbed through the skin.  The study was commissioned by EUON and carried out by the RPA consortium of Triskelion and the Dutch National Institute for Public Health and the Environment (RIVM).  According to EUON, the study found that the lack of standardized,...

On May 5, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “NanoApp helps navigate legal obligations under REACH.”  Olivier de Matos, Secretary General of the European Center for Ecotoxicology and Toxicology (ECETOC), describes the web-based app that was designed to help registrants follow the European Chemicals Agency’s (ECHA) guidance on sets of nanoforms.  According to de Matos, the app primarily covers the “Appendix for...

On April 7, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Carbon Nanotubes — First nanomaterial of high concern on the SIN List.”  As reported in our November 27, 2019, blog item, ChemSec added carbon nanotubes to the Substitute It Now (SIN) List in November 2019.  According to Dr. Anna Lennquist, Senior Toxicologist, International Chemical Secretariat (ChemSec), ever since ChemSec created the SIN List, there have been...

The European Union (EU) Observatory for Nanomaterials (EUON) posted an article on April 6, 2020, announcing the availability of a study that found a lack of data on female fertility.  The study, A critical review of studies on the reproductive and developmental toxicity of nanomaterials, was commissioned by the European Chemicals Agency (ECHA) and carried out by DHI A/S and the Danish National Research Center for the Working Environment.  The scope of this project was to...

On March 3, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “‘Nanoplastics’ — it’s a name game.”  Claire Skentelbery, Director General, Nanotechnology Industries Association (NIA), reviews the difference between engineered (manufactured) nanomaterials and naturally originating (incidental) nanomaterials.  Skentelbery notes that use of the term “nanoplastics,” without describing their origins, “risks the perception...

On December 11, 2019, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “The innovator, the regulator and the citizen — building public trust through transparent, empowered and safe innovation.”  Carlos Eduardo Lima da Cunha, the European Commission (EC), explains how the EU is supporting safe by design approaches to new technologies such as nanomaterials to deliver safer products to the market.  Lima da Cunha notes that the EU has...